[1]吕树文,孙　刚,张加勇,等.硝基苯对鸭免疫器官及禽流感免疫应答的影响[J].黑龙江农业科学,2009,(01):110-112.
　Lv Shu-wen,SUN Gang,ZHANG Jia-yong,et al.Effect of Nitrobenzene Toxication on ImmuneOrgans and Function inAvian Influenza Immune Response in Duck[J].HEILONGJIANG AGRICULTURAL SCIENCES,2009,(01):110-112.
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硝基苯对鸭免疫器官及禽流感免疫应答的影响

《黑龙江农业科学》[ISSN:1002-2767/CN:23-1204/S] 卷: 期数: 2009年01 页码: 110-112 栏目: 出版日期: 2009-01-10
Title:
Effect of Nitrobenzene Toxication on ImmuneOrgans and Function inAvian Influenza Immune Response in Duck
文章编号:
1002-2767(2009)01-0110-03
作者:
吕树文1 ;  孙　刚2 ;  张加勇2 ;  刘　娣3
(1 .大庆石油管理局供水公司, 黑龙江大庆163451;2 .黑龙江省动物卫生监督所, 黑龙江哈尔滨150090 ;3 .东北林业大学博士后流动站、黑龙江省农业科学院博士后工作站,黑龙江哈尔滨150086)
Author(s):
Lv Shu-wen1 ;  SUN Gang2 ;  ZHANG Jia-yong2 ; LIU Di3
1 .Water Supply Corporation of Petroleum Administ ration Bureau in Daqing , Daqing , Heilongjiang163451 ;2 .Heilongjiang Institute of Animal Health Inspection , Harbin ,Heilongjiang 150090 ;3 .PostdoctorResearch Station In Northeast Forest ry University , Postdoctor Research Station In Heilongjiang Academyof Agricultural Sciences,Harbin ,Heilongjiang 150086
关键词:
鸭; 硝基苯; 免疫器官; 禽流感; 免疫应答
Keywords:
ducks; nitrobenzene ; immune organ; avian influenza ; immune response
分类号:
S834
文献标志码:
A
摘要:
为探讨硝基苯对鸭免疫器官及免疫应答的影响, 以鸭为试验动物, 按53.66 mg ·kg -1 灌胃硝基苯, 复制鸭硝基苯中毒及模型。结果表明:(1)硝基苯对免疫器官发育及体液免疫功能造成广泛的抑制效应。(2)硝基苯影响了禽流感抗体的产生, 并在较低的水平上维持。(3)硝基苯中毒组胸腺、脾脏、法氏囊脏器指数均低于对照组,(4)硝基苯中毒组鸭胸腺、脾脏、法氏囊出现广泛实质性变化, 包括淋巴细胞数量显著减少、变性、坏死、滤泡减少或无滤泡形成, 胸腺皮质萎缩。
Abstract:
In this paper , ducks were allocated into two groups, the ducks in the contrast g roup were only fed with the basic diet, the poisoning group was fed with the diet supplemented with 53.66 mg ·kg -1 nitrobenzene.Ducks of the poisoning groupshowed ducks sig ns of nitrobenzene toxication.Ducks to xicology model caused by subchro nic nitrobenzene toxication wasdeeply studied trough clinical finding s, pathohistological changes, the ELISA of AI and the measurement of thymus, spleenand bursa of FAB.The result showed (1)From o rganizing pathology , clinical symptom index to observation, nitrobenzenetoxication has caused the ex tensive restrain effect to immune o rgan develo pment and immune function.(2)Nitrobenzene to xicationhas influenced the productio n of the antibody seriously , and kept on the relatively low level.The reducing of the antibodyELISA result titer of AI proved that the immune function received the obvious injury at the same time.(3)Thymus,spleen and brusal in group nitrobenzene toxication organs indexes were lower than those of the contrast g roup.It proved thatthe nitrobenzene w ould suppress the growing of immune organ seriously .(4)Immune organ in histology was observed, includinglymphocy te reduce notably by quantity , necrosis, straining and steep strainedding and steep fo rming .

参考文献/References:

[ 1] 　江泉观, 纪云晶, 常元勋.环境化学毒物防止手册[ M] .化学工业出版社.2004:724-725.

[ 2] 　马汐平, 付宝荣, 刘洁, 等.制药废水中硝基苯致突性的细菌检测试验[ J] .辽宁大学学报, 1999 ,26(2):175-178.
[ 3] 　Hankenson K, Schaeff er D J.Microt ox assay of trini-t rotoluene, diaminonitrotoluene and dinitromethylalanine mixtures[ J] .Bull Envi ronCont am Toxicol ,1991 ,46(4):550-553 .
[ 4] 　刘伯臣,邢厚娟, 丁岚峰, 等.硝基苯对小鼠脾的毒性作用[ J] .中国兽医科学,2008, 38(04):355-359).
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备注/Memo

第一作者简介:吕树文(1965-), 男, 黑龙江人, 大专,畜牧师, 从事畜牧科技推广工作。Tel :13836103861 , 82388735 ;E-mail:sungang2006@yahoo .com.cn 。

更新日期/Last Update: 2016-05-23