YANG Guo-wei.Effects of NCOA1, OPN?and RBP4Genes on Birth Weight and Weight on 30 d in Piglet[J].HEILONGJIANG AGRICULTURAL SCIENCES,2010,(06):5-7.
NCOA1、OPN和RBP4基因对仔猪初生重和30日龄体重的影响
- Title:
- Effects of NCOA1, OPN?and RBP4Genes on Birth Weight and Weight on 30 d in Piglet
- 文章编号:
- 1002-2767（2010）06-0005-03
- 分类号:
- S813.1
- 文献标志码:
- A
- 摘要:
- 采用PCR-RFLP方法检测了NCOA1基因，OPN基因和RBP4基因的多态性，并且分析了不同基因型对仔猪出生重和30日龄体重效应的大小。结果表明：NCOA1基因可显著影响仔猪的30日龄体重，AA型个体比BB型个体增重显著（P＜0.05）。而OPN和RBP4基因的不同基因型对这2个性状的效应差异均不显著。在试验群体内，NCOA1基因可作为一个有效的候选基因进行研究应用，而OPN和RBP4基因还需进一步扩大样本量进行相关性分析。
- Abstract:
- The polymorphism of nuclear receptor coactivator 1 gene (NCOA1), osteopontin (OPN) and retinol-binding protein 4 (RBP4) genes were tested by PCR-RFLP and the relationship between genotypes and birth weight, litter weight on 30 d was analyzed. The results showed that NCOA1 had a moderate effect on the weight on 30 d trait, AA genotype could significantly increased the weight(P＜0.05) compared with AB and BB genotype, but OPN and RBP4 genes had no effect on these two trait. In this experiment group, NCOA1 could be seen as an effective candidate gene in future research and application, but OPN and RBP4 needed more associatively analysis in larger sample.
参考文献/References:
[1]Melville J S, Gibbins A M V, Robinson J A B, et al. A eishan positive QTL for prolificacy traits found at the NCOA1 locus on SSC 3 [C]// 7th World Congress on Genetics Applied to Livestock Production. Montpellier,2002. [2]何荣环，黄荷凤. 骨桥蛋白与生殖[J].国外医学(计划生育分册)，2004，23(2)：99-101. [3]Trout W E, Mcdonnell J J, Kramer K K, et al. The retinol-binding protein of the expanding pig blastocyst: molecular cloning and expression in trophectoderm and embryonic disc[J]. Molecular Endocrinology, 1991, 5: 1533-1540. [4]施启顺，柳小春，刘志伟，等. 5个与猪产仔数相关基因的效应分析[J]. 遗传，2006，28(6)：652-658. [5]Knoll A, Stratil A, Cepica S, et al. Length polymorphism in an intron of the porcine osteopontin (SPP1) gene is caused by the presence or absence of a SINE (PRE-1) element [J]. Anim Genet, 1999, 30(6):466. [6]罗仍卓么，王立贤，孙世铎. 猪OPN基因与繁殖性状的关联分析[J]. 农业生物技术学报，2008，16(3)：412-416. [7]Rothschild M F, Messer L, Day A, et al. Investigation of the retinol-binding protein 4 (RBP4) gene as a candidate gene for increased litter size in pigs [J]. Mammalian Genome, 2000, 11(1): 75-77. [8]Drogemuller C, Hamann H, Distl O. Candidate gene markers for litter size in different German pig lines[J]. Journal of Animal Science, 2001, 79: 2565-2570.
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备注/Memo
基金项目： “十一五”国家科技支撑计划重点资助项目（2008BADB2B02）