[1]王晖,高德满,高妍夏,等.七种药用植物c4h基因密码子偏好性及聚类分析[J].黑龙江农业科学,2015,(03):5-8.[doi:10.11942/j.issn1002-2767.2015.03.0005]
　WANG Hui,GAO De man,GAO Yan xia,et al.Codon Usage Bias and Cluster Analysis of c4h Genes in Seven Medicinal Plants[J].HEILONGJIANG AGRICULTURAL SCIENCES,2015,(03):5-8.[doi:10.11942/j.issn1002-2767.2015.03.0005]
点击复制

七种药用植物c4h基因密码子偏好性及聚类分析

《黑龙江农业科学》[ISSN:1002-2767/CN:23-1204/S] 卷: 期数: 2015年03 页码: 5-8 栏目: 出版日期: 2015-03-10
Title:
Codon Usage Bias and Cluster Analysis of c4h Genes in Seven Medicinal Plants
文章编号:
1002-2767（2015）03000504
作者:
王晖1; 高德满2; 高妍夏1; 李学军3 ; 马博辉4; 杨贵明1
1.承德医学院 蚕业研究所，河北省高校特产蚕桑应用技术研发中心，河北 承德 067000； 2.锡林郭勒盟第二中学，内蒙古 锡林浩特 026000； 3.承德医学院 中药研究所，河北 承德 067000； 4.承德医学院 图书馆，河北 承德 067000
Author(s):
WANG Hui1; GAO Deman2; GAO Yanxia1; LI Xuejun3; MA Bohui4; YANG Guiming1
1.The Sericultural Research Institute，Hebei Universities Technology Research and Development Center of Sericulture,Chengde Medical University,Chengde,Hebei 067000; 2.The Second Middle School of Xilingol League,Xilinhot,Inner Mongolia 026000; 3.Institute of Chinese Traditional Medicine,Chengde Medical University,Chengde,Hebei 067000; 4.Library of Chengde Medical University,Chengde,Hebei 067000
关键词:
c4h基因; 密码子偏好性; 聚类分析
Keywords:
c4h genes;  codon bias;  cluster analysis
分类号:
Q949.95
DOI:
10.11942/j.issn1002-2767.2015.03.0005
文献标志码:
A
摘要:
为了深入研究药用植物基因特性，利用CodonW和SPSS18.0软件对丹参、黄芪、黄芩、忍冬、桑树、野甘草、长春花共7种药用植物c4h基因密码子进行偏好性和聚类分析。结果表明：7种药用植物c4h基因的有效密码子数介于46.1～55.92，密码子使用偏好性弱，5种药用植物倾向于GC结尾的密码子，2种倾向于AT结尾的密码子。7种药用植物经聚类分析分为两大类，长春花与黄芪为一大类，另一大类中，丹参与黄芩为一类，野甘草、桑树和忍冬为一类。
Abstract:
In order to further study genetic features of medicinal plants,coding usage of c4h genes in medicial plants including Salvia miltiorrhiza,Catharanthus roseus,Scoparia dulcis,Scutellaria baicalensis,Morus alba,Astragalus mongholicus,Lonicera japonica were analyzed by CodonW.Cluster analysis of c4h genes codon bias were carried out by SPSS18.0.The result showed that c4h genes ENc were between 46.1 and 55.92 in seven medical plants,they had a weak codon bias,5 medicinal plants tended to use codon ending with GC,2 medicinal plants tends to use codon ending with AT.Seven medicinal plants were divided into two parts,one part included Catharanthus roseus and Astragalus mongholicus.In the other part,Salvia miltiorrhiza and Scutellaria baicalensis were in a group,Scoparia dulcis,Morus alba and Lonicera japonica were in another group.

参考文献/References:

［1］王树斌,全雪丽,具红光,等.膜荚黄芪肉桂酸4羟化酶(c4h)基因克隆与序列分析\[J\].延边大学农学学报,2012,34(4):277281.
[2]Hu C,Chen J,Ye L,et al.Codon usage bias in human cytomegalovirus and its biological implication[J].Gene,2014,545(1):514.
[3]Mazumder T H,Chakraborty S,Paul P.A cross talk between codon usage bias in human oncogenes[J].Bioinformation,2014,10(5):256262.
[4]Chen H,Sun S,Norenburg J L,et al.Mutation and selection cause codon usage and bias in mitochondrial genomes of ribbon worms(Nemertea)[J].PLOS ONE,2014,9(1):e85631.
[5]Mirsafian H,Mat Ripen A,Singh A,et al.A comparative analysis of synonymous codon usage bias pattern in human albumin superfamily[J].The Scientific World Journal,2013,2014:639682.
[6]Behura S K,Severson D W.Codon usage bias: causative factors,quantification methods and genomewide patterns: with emphasis on insect genomes[J].Biological Reviews,2013,88(1):4961.

备注/Memo

王晖（1985-），男，山西省大同县人，硕士，研究实习员，从事生物学相关研究。Email：wanghui861@126.com。

更新日期/Last Update: 2015-05-26